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In silico Experimentation of Glioma Microenvironment Development and Anti-tumor Therapy

Tumor cells do not develop in isolation, but co-evolve with stromal cells and tumor-associated immune cells in a tumor microenvironment mediated by an array of soluble factors, forming a complex intercellular signaling network. Herein, we report an unbiased, generic model to integrate prior biochemi...

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Detalles Bibliográficos
Autores principales: Wu, Yu, Lu, Yao, Chen, Weiqiang, Fu, Jianping, Fan, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271023/
https://www.ncbi.nlm.nih.gov/pubmed/22319429
http://dx.doi.org/10.1371/journal.pcbi.1002355