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In silico Experimentation of Glioma Microenvironment Development and Anti-tumor Therapy
Tumor cells do not develop in isolation, but co-evolve with stromal cells and tumor-associated immune cells in a tumor microenvironment mediated by an array of soluble factors, forming a complex intercellular signaling network. Herein, we report an unbiased, generic model to integrate prior biochemi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271023/ https://www.ncbi.nlm.nih.gov/pubmed/22319429 http://dx.doi.org/10.1371/journal.pcbi.1002355 |