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Remobilization of Sleeping Beauty transposons in the germline of Xenopus tropicalis

BACKGROUND: The Sleeping Beauty (SB) transposon system has been used for germline transgenesis of the diploid frog, Xenopus tropicalis. Injecting one-cell embryos with plasmid DNA harboring an SB transposon substrate together with mRNA encoding the SB transposase enzyme resulted in non-canonical int...

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Detalles Bibliográficos
Autores principales: Yergeau, Donald A, Kelley, Clair M, Kuliyev, Emin, Zhu, Haiqing, Johnson Hamlet, Michelle R, Sater, Amy K, Wells, Dan E, Mead, Paul E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271037/
https://www.ncbi.nlm.nih.gov/pubmed/22115366
http://dx.doi.org/10.1186/1759-8753-2-15