Clonal Immune Responses of Mycobacterium-Specific γδ T Cells in Tuberculous and Non-Tuberculous Tissues during M. tuberculosis Infection

BACKGROUND: We previously demonstrated that unvaccinated macaques infected with large-dose M.tuberculosis(Mtb) exhibited delays for pulmonary trafficking of Ag-specific αβ and γδ T effector cells, and developed severe lung tuberculosis(TB) and “secondary” Mtb infection in remote organs such as liver...

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Detalles Bibliográficos
Autores principales: Huang, Dan, Chen, Crystal Y., Zhang, Meihong, Qiu, Liyou, Shen, Yun, Du, George, Zhou, Keyuan, Wang, Richard, Chen, Zheng W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271047/
https://www.ncbi.nlm.nih.gov/pubmed/22319574
http://dx.doi.org/10.1371/journal.pone.0030631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271047/
https://www.ncbi.nlm.nih.gov/pubmed/22319574
http://dx.doi.org/10.1371/journal.pone.0030631

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