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Clonal Immune Responses of Mycobacterium-Specific γδ T Cells in Tuberculous and Non-Tuberculous Tissues during M. tuberculosis Infection
BACKGROUND: We previously demonstrated that unvaccinated macaques infected with large-dose M.tuberculosis(Mtb) exhibited delays for pulmonary trafficking of Ag-specific αβ and γδ T effector cells, and developed severe lung tuberculosis(TB) and “secondary” Mtb infection in remote organs such as liver...
Autores principales: | Huang, Dan, Chen, Crystal Y., Zhang, Meihong, Qiu, Liyou, Shen, Yun, Du, George, Zhou, Keyuan, Wang, Richard, Chen, Zheng W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271047/ https://www.ncbi.nlm.nih.gov/pubmed/22319574 http://dx.doi.org/10.1371/journal.pone.0030631 |
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