The Empirical Power of Rare Variant Association Methods: Results from Sanger Sequencing in 1,998 Individuals

The role of rare genetic variation in the etiology of complex disease remains unclear. However, the development of next-generation sequencing technologies offers the experimental opportunity to address this question. Several novel statistical methodologies have been recently proposed to assess the c...

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Detalles Bibliográficos
Autores principales: Ladouceur, Martin, Dastani, Zari, Aulchenko, Yurii S., Greenwood, Celia M. T., Richards, J. Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271058/
https://www.ncbi.nlm.nih.gov/pubmed/22319458
http://dx.doi.org/10.1371/journal.pgen.1002496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271058/
https://www.ncbi.nlm.nih.gov/pubmed/22319458
http://dx.doi.org/10.1371/journal.pgen.1002496

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