Cargando…

Viral Cyclins Mediate Separate Phases of Infection by Integrating Functions of Distinct Mammalian Cyclins

Gammaherpesvirus cyclins have expanded biochemical features relative to mammalian cyclins, and promote infection and pathogenesis including acute lung infection, viral persistence, and reactivation from latency. To define the essential features of the viral cyclin, we generated a panel of knock-in v...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Katherine S., Suarez, Andrea L., Claypool, David J., Armstrong, Taylor K., Buckingham, Erin M., van Dyk, Linda F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271081/
https://www.ncbi.nlm.nih.gov/pubmed/22319441
http://dx.doi.org/10.1371/journal.ppat.1002496