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Ovotoxic Effects of Galactose Involve Attenuation of Follicle-Stimulating Hormone Bioactivity and Up-Regulation of Granulosa Cell p53 Expression

Clinical evidence suggests an association between galactosaemia and premature ovarian insufficiency (POI); however, the mechanism still remains unresolved. Experimental galactose toxicity in rats produces an array of ovarian dysfunction including ovarian development with deficient follicular reserve...

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Detalles Bibliográficos
Autores principales: Banerjee, Sayani, Chakraborty, Pratip, Saha, Piyali, Bandyopadhyay, Soma Aditya, Banerjee, Sutapa, Kabir, Syed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271100/
https://www.ncbi.nlm.nih.gov/pubmed/22319579
http://dx.doi.org/10.1371/journal.pone.0030709