Cargando…

InsR/FoxO1 Signaling Curtails Hypothalamic POMC Neuron Number

Insulin receptor (InsR) signaling through transcription factor FoxO1 is important in the development of hypothalamic neuron feeding circuits, but knowledge about underlying mechanisms is limited. To investigate the role of InsR/FoxO1 signaling in the development and maintenance of these circuits, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Plum, Leona, Lin, Hua V., Aizawa, Kumiko S., Liu, Yitian, Accili, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271107/
https://www.ncbi.nlm.nih.gov/pubmed/22319636
http://dx.doi.org/10.1371/journal.pone.0031487