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Vaccine Protection Against Acquisition of Neutralization-Resistant SIV Challenges in Rhesus Monkeys

Preclinical studies of HIV-1 vaccine candidates have typically shown post-infection virologic control, but protection against acquisition of infection has previously only been reported against neutralization-sensitive virus challenges(1–3). Here we demonstrate vaccine protection against acquisition...

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Detalles Bibliográficos
Autores principales: Barouch, Dan H., Liu, Jinyan, Li, Hualin, Maxfield, Lori F., Abbink, Peter, Lynch, Diana M., Iampietro, M. Justin, SanMiguel, Adam, Seaman, Michael S., Ferrari, Guido, Forthal, Donald N., Ourmanov, Ilnour, Hirsch, Vanessa M., Carville, Angela, Mansfield, Keith G., Stablein, Donald, Pau, Maria G., Schuitemaker, Hanneke, Sadoff, Jerald C., Billings, Erik M., Rao, Mangala, Robb, Merlin L., Kim, Jerome H., Marovich, Mary A., Goudsmit, Jaap, Michael, Nelson L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271177/
https://www.ncbi.nlm.nih.gov/pubmed/22217938
http://dx.doi.org/10.1038/nature10766