Wnt7a/Fzd7 Signalling Directly Activates the Akt/mTOR Anabolic Growth Pathway in Skeletal Muscle

Wnt7a signals through its receptor Fzd7 to activate the planar-cell-polarity pathway and drive the symmetric expansion of satellite stem cells resulting in enhanced repair of skeletal muscle. In differentiated myofibres, we observed that Wnt7a binding to Fzd7 directly activates the Akt/mTOR growth p...

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Detalles Bibliográficos
Autores principales: von Maltzahn, Julia, Bentzinger, C. Florian, Rudnicki, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271181/
https://www.ncbi.nlm.nih.gov/pubmed/22179044
http://dx.doi.org/10.1038/ncb2404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271181/
https://www.ncbi.nlm.nih.gov/pubmed/22179044
http://dx.doi.org/10.1038/ncb2404

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