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Pharmacokinetics of venlafaxine and its major metabolite o-desmethylvenlafaxine in freely moving mice using automated dosing/sampling system

OBJECTIVE: To assess the pharmacokinetics of venlafaxine (VEN) and its major metabolite o-desmethylvenlafaxine (ODV) in freely moving mice using automated dosing/infusion (ADI) and automated blood sampling (ABS) systems. In addition, concentration of VEN and its metabolite ODV were also measured in...

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Detalles Bibliográficos
Autores principales: Aryal, Bijay, Aryal, Dipendra, Kim, Eun-Joo, Kim, Hyung-Gun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271533/
https://www.ncbi.nlm.nih.gov/pubmed/22345864
http://dx.doi.org/10.4103/0253-7613.91861