An unanticipated architecture of the 750 kD holoenzyme of 3-methylcrotonyl-CoA carboxylase

3-methylcrotonyl-CoA carboxylase (MCC), a member of the biotin-dependent carboxylase superfamily, is essential for the metabolism of leucine, and deficient mutations in this enzyme are linked to methylcrotonylglycinuria (MCG) and other serious diseases in humans (1–8). MCC has strong sequence conser...

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Detalles Bibliográficos
Autores principales: Huang, Christine S., Ge, Peng, Zhou, Z. Hong, Tong, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271731/
https://www.ncbi.nlm.nih.gov/pubmed/22158123
http://dx.doi.org/10.1038/nature10691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271731/
https://www.ncbi.nlm.nih.gov/pubmed/22158123
http://dx.doi.org/10.1038/nature10691

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