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New insights regarding HCV-NS5A structure/function and indication of genotypic differences

BACKGROUND: HCV is prevalent throughout the world. It is a major cause of chronic liver disease. There is no effective vaccine and the most common therapy, based on Peginterferon, has a success rate of ~50%. The mechanisms underlying viral resistance have not been elucidated but it has been suggeste...

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Detalles Bibliográficos
Autores principales: Yamasaki, Lilian HT, Arcuri, Helen A, Jardim, Ana Carolina G, Bittar, Cintia, de Carvalho-Mello, Isabel Maria VG, Rahal, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271958/
https://www.ncbi.nlm.nih.gov/pubmed/22239820
http://dx.doi.org/10.1186/1743-422X-9-14