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New insights regarding HCV-NS5A structure/function and indication of genotypic differences
BACKGROUND: HCV is prevalent throughout the world. It is a major cause of chronic liver disease. There is no effective vaccine and the most common therapy, based on Peginterferon, has a success rate of ~50%. The mechanisms underlying viral resistance have not been elucidated but it has been suggeste...
Autores principales: | Yamasaki, Lilian HT, Arcuri, Helen A, Jardim, Ana Carolina G, Bittar, Cintia, de Carvalho-Mello, Isabel Maria VG, Rahal, Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271958/ https://www.ncbi.nlm.nih.gov/pubmed/22239820 http://dx.doi.org/10.1186/1743-422X-9-14 |
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