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Sex-specific association of ACAT-1 rs1044925 SNP and serum lipid levels in the hypercholesterolemic subjects

BACKGROUND: Acyl-CoA:cholesterol acyltransferase (ACAT) is a key enzyme in cellular cholesterol homeostasis and in atherosclerosis. The cellular cholesterol efflux correlated with serum high-density lipoprotein cholesterol (HDL-C) concentrations has shown to be impaired in hyperlipidemic mice. The p...

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Detalles Bibliográficos
Autores principales: Wu, Dong-Feng, Yin, Rui-Xing, Aung, Lynn Htet Htet, Li, Qing, Yan, Ting-Ting, Zeng, Xiao-Na, Huang, Ke-Ke, Huang, Ping, Wu, Jin-Zhen, Pan, Shang-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271972/
https://www.ncbi.nlm.nih.gov/pubmed/22243772
http://dx.doi.org/10.1186/1476-511X-11-9