Knockdown of menin affects pre-mRNA processing and promoter fidelity at the interferon-gamma inducible IRF1 gene

BACKGROUND: The tumor suppressor menin (MEN1) is mutated in the inherited disease multiple endocrine neoplasia type I, and has several documented cellular roles, including the activation and repression of transcription effected by several transcription factors. As an activator, MEN1 is a component o...

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Detalles Bibliográficos
Autores principales: Auriemma, Lauren B, Shah, Shaili, Linden, Lara M, Henriksen, Melissa A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271985/
https://www.ncbi.nlm.nih.gov/pubmed/22240255
http://dx.doi.org/10.1186/1756-8935-5-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271985/
https://www.ncbi.nlm.nih.gov/pubmed/22240255
http://dx.doi.org/10.1186/1756-8935-5-2

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