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The response of early neural genes to FGF signaling or inhibition of BMP indicate the absence of a conserved neural induction module

BACKGROUND: The molecular mechanism that initiates the formation of the vertebrate central nervous system has long been debated. Studies in Xenopus and mouse demonstrate that inhibition of BMP signaling is sufficient to induce neural tissue in explants or ES cells respectively, whereas studies in ch...

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Detalles Bibliográficos
Autores principales: Rogers, Crystal D, Ferzli, George S, Casey, Elena S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271986/
https://www.ncbi.nlm.nih.gov/pubmed/22172147
http://dx.doi.org/10.1186/1471-213X-11-74