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Effects of cyclin-dependent kinase 8 specific siRNA on the proliferation and apoptosis of colon cancer cells
BACKGROUND: To investigate the expression of cyclin-dependent kinase 8 (CDK8) and β-catenin in colon cancer and evaluate the role of CDK8 in the proliferation, apoptosis and cell cycle progression of colon cancer cells, especially in HCT116 cell line. METHODS: Colon cancer cell line HCT116 was trans...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271993/ https://www.ncbi.nlm.nih.gov/pubmed/22104393 http://dx.doi.org/10.1186/1756-9966-30-109 |