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Effects of cyclin-dependent kinase 8 specific siRNA on the proliferation and apoptosis of colon cancer cells

BACKGROUND: To investigate the expression of cyclin-dependent kinase 8 (CDK8) and β-catenin in colon cancer and evaluate the role of CDK8 in the proliferation, apoptosis and cell cycle progression of colon cancer cells, especially in HCT116 cell line. METHODS: Colon cancer cell line HCT116 was trans...

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Detalles Bibliográficos
Autores principales: He, Song-Bing, Yuan, Yin, Wang, Lei, Yu, Min-Jing, Zhu, Yi-Bei, Zhu, Xing-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271993/
https://www.ncbi.nlm.nih.gov/pubmed/22104393
http://dx.doi.org/10.1186/1756-9966-30-109