Hydroxyl Radical Modification of Collagen Type II Increases Its Arthritogenicity and Immunogenicity

BACKGROUND: The oxidation of proteins by endogenously generated free radicals causes structural modifications in the molecules that lead to generation of neo-antigenic epitopes that have implications in various autoimmune disorders, including rheumatoid arthritis (RA). Collagen induced arthritis (CI...

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Detalles Bibliográficos
Autores principales: Shahab, Uzma, Ahmad, Saheem, Moinuddin, Dixit, Kiran, Habib, Safia, Alam, Khursheed, Ali, Asif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272010/
https://www.ncbi.nlm.nih.gov/pubmed/22319617
http://dx.doi.org/10.1371/journal.pone.0031199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272010/
https://www.ncbi.nlm.nih.gov/pubmed/22319617
http://dx.doi.org/10.1371/journal.pone.0031199

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