Cargando…
Hydroxyl Radical Modification of Collagen Type II Increases Its Arthritogenicity and Immunogenicity
BACKGROUND: The oxidation of proteins by endogenously generated free radicals causes structural modifications in the molecules that lead to generation of neo-antigenic epitopes that have implications in various autoimmune disorders, including rheumatoid arthritis (RA). Collagen induced arthritis (CI...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272010/ https://www.ncbi.nlm.nih.gov/pubmed/22319617 http://dx.doi.org/10.1371/journal.pone.0031199 |