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Klotho Lacks a Vitamin D Independent Physiological Role in Glucose Homeostasis, Bone Turnover, and Steady-State PTH Secretion In Vivo

Apart from its function as co-receptor for fibroblast growth factor-23 (FGF23), Klotho is thought to regulate insulin signaling, intracellular oxidative stress, and parathyroid hormone (PTH) secretion in an FGF23 independent fashion. Here, we crossed Klotho deficient (Kl(−/−)) mice with vitamin D re...

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Detalles Bibliográficos
Autores principales: Anour, René, Andrukhova, Olena, Ritter, Eva, Zeitz, Ute, Erben, Reinhold G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272012/
https://www.ncbi.nlm.nih.gov/pubmed/22319626
http://dx.doi.org/10.1371/journal.pone.0031376