Novel Functional MAR Elements of Double Minute Chromosomes in Human Ovarian Cells Capable of Enhancing Gene Expression

Double minute chromosomes or double minutes (DMs) are cytogenetic hallmarks of extrachromosomal genomic amplification and play a critical role in tumorigenesis. Amplified copies of oncogenes in DMs have been associated with increased growth and survival of cancer cells but DNA sequences in DMs which...

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Detalles Bibliográficos
Autores principales: Jin, Yan, Liu, Zheng, Cao, Wei, Ma, Xinying, Fan, Yihui, Yu, Yang, Bai, Jing, Chen, Feng, Rosales, Jesusa, Lee, Ki-Young, Fu, Songbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272018/
https://www.ncbi.nlm.nih.gov/pubmed/22319568
http://dx.doi.org/10.1371/journal.pone.0030419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272018/
https://www.ncbi.nlm.nih.gov/pubmed/22319568
http://dx.doi.org/10.1371/journal.pone.0030419

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