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Novel Functional MAR Elements of Double Minute Chromosomes in Human Ovarian Cells Capable of Enhancing Gene Expression
Double minute chromosomes or double minutes (DMs) are cytogenetic hallmarks of extrachromosomal genomic amplification and play a critical role in tumorigenesis. Amplified copies of oncogenes in DMs have been associated with increased growth and survival of cancer cells but DNA sequences in DMs which...
Autores principales: | Jin, Yan, Liu, Zheng, Cao, Wei, Ma, Xinying, Fan, Yihui, Yu, Yang, Bai, Jing, Chen, Feng, Rosales, Jesusa, Lee, Ki-Young, Fu, Songbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272018/ https://www.ncbi.nlm.nih.gov/pubmed/22319568 http://dx.doi.org/10.1371/journal.pone.0030419 |
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