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Complexity of Murine Cardiomyocyte miRNA Biogenesis, Sequence Variant Expression and Function

microRNAs (miRNAs) are critical to heart development and disease. Emerging research indicates that regulated precursor processing can give rise to an unexpected diversity of miRNA variants. We subjected small RNA from murine HL-1 cardiomyocyte cells to next generation sequencing to investigate the r...

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Detalles Bibliográficos
Autores principales: Humphreys, David T., Hynes, Carly J., Patel, Hardip R., Wei, Grace H., Cannon, Leah, Fatkin, Diane, Suter, Catherine M., Clancy, Jennifer L., Preiss, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272019/
https://www.ncbi.nlm.nih.gov/pubmed/22319597
http://dx.doi.org/10.1371/journal.pone.0030933