Benzo[a]pyrene, Aflatoxine B(1) and Acetaldehyde Mutational Patterns in TP53 Gene Using a Functional Assay: Relevance to Human Cancer Aetiology

Mutations in the TP53 gene are the most common alterations in human tumours. TP53 mutational patterns have sometimes been linked to carcinogen exposure. In hepatocellular carcinoma, a specific G>T transversion on codon 249 is classically described as a fingerprint of aflatoxin B(1) exposure. Like...

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Detalles Bibliográficos
Autores principales: Paget, Vincent, Lechevrel, Mathilde, André, Véronique, Le Goff, Jérémie, Pottier, Didier, Billet, Sylvain, Garçon, Guillaume, Shirali, Pirouz, Sichel, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272023/
https://www.ncbi.nlm.nih.gov/pubmed/22319594
http://dx.doi.org/10.1371/journal.pone.0030921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272023/
https://www.ncbi.nlm.nih.gov/pubmed/22319594
http://dx.doi.org/10.1371/journal.pone.0030921

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