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Bezielle Selectively Targets Mitochondria of Cancer Cells to Inhibit Glycolysis and OXPHOS

Bezielle (BZL101) is a candidate oral drug that has shown promising efficacy and excellent safety in the early phase clinical trials for advanced breast cancer. Bezielle is an aqueous extract from the herb Scutellaria barbata. We have reported previously that Bezielle was selectively cytotoxic to ca...

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Detalles Bibliográficos
Autores principales: Chen, Vivian, Staub, Richard E., Fong, Sylvia, Tagliaferri, Mary, Cohen, Isaac, Shtivelman, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272024/
https://www.ncbi.nlm.nih.gov/pubmed/22319564
http://dx.doi.org/10.1371/journal.pone.0030300