Mre11 regulates CtIP–dependent double strand break repair by interaction with CDK2

Homologous recombination (HR) facilitates accurate repair of DNA double strand breaks (DSBs) during S and G2 phases of the cell cycle by using intact sister chromatids as sequence templates. HR capacity is maximized in S and G2 by Cyclin–Dependent Kinase (CDK) phosphorylation of CtIP, which subseque...

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Detalles Bibliográficos
Autores principales: Buis, Jeffrey, Stoneham, Trina, Spehalski, Elizabeth, Ferguson, David O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272152/
https://www.ncbi.nlm.nih.gov/pubmed/22231403
http://dx.doi.org/10.1038/nsmb.2212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272152/
https://www.ncbi.nlm.nih.gov/pubmed/22231403
http://dx.doi.org/10.1038/nsmb.2212

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