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Mre11 regulates CtIP–dependent double strand break repair by interaction with CDK2

Homologous recombination (HR) facilitates accurate repair of DNA double strand breaks (DSBs) during S and G2 phases of the cell cycle by using intact sister chromatids as sequence templates. HR capacity is maximized in S and G2 by Cyclin–Dependent Kinase (CDK) phosphorylation of CtIP, which subseque...

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Detalles Bibliográficos
Autores principales:	Buis, Jeffrey, Stoneham, Trina, Spehalski, Elizabeth, Ferguson, David O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272152/ https://www.ncbi.nlm.nih.gov/pubmed/22231403 http://dx.doi.org/10.1038/nsmb.2212

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