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Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility

Heterogeneity of embryological origins is a hallmark of vascular smooth muscle cells (SMCs), which may influence vascular disease development. Differentiation of human pluripotent stem cells (hPSCs) into developmental origin-specific SMC subtypes remains elusive. In this study, we have established a...

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Detalles Bibliográficos
Autores principales: Cheung, Christine, Bernardo, Andreia S, Trotter, Matthew W B, Pedersen, Roger A, Sinha, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272383/
https://www.ncbi.nlm.nih.gov/pubmed/22252507
http://dx.doi.org/10.1038/nbt.2107