Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

Oestrogen receptor-α (ER) is the defining and driving transcription factor in the majority of breast cancers and its target genes dictate cell growth and endocrine response, yet genomic understanding of ER function has been restricted to model systems(1-3). We now map genome-wide ER binding events,...

Descripción completa

Detalles Bibliográficos
Autores principales: Ross-Innes, Caryn S., Stark, Rory, Teschendorff, Andrew E., Holmes, Kelly A., Ali, H. Raza, Dunning, Mark J., Brown, Gordon D., Gojis, Ondrej, Ellis, Ian O., Green, Andrew R., Ali, Simak, Chin, Suet-Feung, Palmieri, Carlo, Caldas, Carlos, Carroll, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272464/
https://www.ncbi.nlm.nih.gov/pubmed/22217937
http://dx.doi.org/10.1038/nature10730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272464/
https://www.ncbi.nlm.nih.gov/pubmed/22217937
http://dx.doi.org/10.1038/nature10730

Ejemplares similares