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Cysteinyl leukotriene type I receptor desensitization sustains Ca(2+)-dependent gene expression

A universal mechanism to turn off a biological response is receptor desensitization, where the ability of a physiological trigger to activate a cell is lost despite the continued presence of the stimulus. Receptor desensitization of G protein-coupled receptors involves uncoupling of the receptor fro...

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Detalles Bibliográficos
Autores principales: Ng, Siaw-Wei, Bakowski, Daniel, Nelson, Charmaine, Mehta, Ravi, Almeyda, Robert, Bates, Grant, Parekh, Anant B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272478/
https://www.ncbi.nlm.nih.gov/pubmed/22230957
http://dx.doi.org/10.1038/nature10731