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Cysteinyl leukotriene type I receptor desensitization sustains Ca(2+)-dependent gene expression
A universal mechanism to turn off a biological response is receptor desensitization, where the ability of a physiological trigger to activate a cell is lost despite the continued presence of the stimulus. Receptor desensitization of G protein-coupled receptors involves uncoupling of the receptor fro...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272478/ https://www.ncbi.nlm.nih.gov/pubmed/22230957 http://dx.doi.org/10.1038/nature10731 |