Evaluation of the neurological safety of epidurally-administered pregabalin in rats

BACKGROUND: The primary site of action of pregabalin, i.e. the α-2-δ subunit of the voltage-dependent calcium channel, is located at the dorsal root ganglion and dorsal horn of the spinal cord. Therefore, the epidural administration of pregabalin could have advantages over oral administration. Howev...

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Detalles Bibliográficos
Autores principales: Lee, Jeong Rim, Lee, Pyung-Bok, Choe, Gheeyoung, Lee, Sang Chul, Lee, Hyo Min, Kim, Eunjung, Kim, Yong Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Anesthesiologists 2012
Materias:
Experimental Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272531/
https://www.ncbi.nlm.nih.gov/pubmed/22323956
http://dx.doi.org/10.4097/kjae.2012.62.1.57

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272531/
https://www.ncbi.nlm.nih.gov/pubmed/22323956
http://dx.doi.org/10.4097/kjae.2012.62.1.57

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