Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor

Albumin is the most abundant protein in blood where it has a pivotal role as a transporter of fatty acids and drugs. Like IgG, albumin has long serum half-life, protected from degradation by pH-dependent recycling mediated by interaction with the neonatal Fc receptor, FcRn. Although the FcRn interac...

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Detalles Bibliográficos
Autores principales: Andersen, Jan Terje, Dalhus, Bjørn, Cameron, Jason, Daba, Muluneh Bekele, Plumridge, Andrew, Evans, Leslie, Brennan, Stephan O., Gunnarsen, Kristin Støen, Bjørås, Magnar, Sleep, Darrell, Sandlie, Inger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272563/
https://www.ncbi.nlm.nih.gov/pubmed/22215085
http://dx.doi.org/10.1038/ncomms1607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272563/
https://www.ncbi.nlm.nih.gov/pubmed/22215085
http://dx.doi.org/10.1038/ncomms1607

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