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Inhibition of cowpox virus and monkeypox virus infection by mitoxantrone

Mitoxantrone, an FDA-approved therapeutic for the treatment of cancer and multiple sclerosis, was previously reported to exhibit antiviral activity against vaccinia virus. To determine whether this activity extends to other orthopoxviruses, mitoxantrone was tested against cowpox and monkeypox. Mitox...

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Detalles Bibliográficos
Autores principales: Altmann, Sharon E., Smith, Alvin L., Dyall, Julie, Johnson, Reed F., Dodd, Lori E., Jahrling, Peter B., Paragas, Jason, Blaney, Joseph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272698/
https://www.ncbi.nlm.nih.gov/pubmed/22182595
http://dx.doi.org/10.1016/j.antiviral.2011.12.001