ATP11c is critical for phosphatidylserine internalization and B lymphocyte differentiation

Subcompartments of the plasma membrane are believed to be critical for lymphocyte responses but few genetic tools exist to test their function. Here we describe a new X-linked B cell deficiency syndrome in mice caused by mutations in Atp11c, a member of the P4 ATPase family thought to serve as flipp...

Descripción completa

Detalles Bibliográficos
Autores principales: Yabas, Mehmet, Teh, Charis E., Frankenreiter, Sandra, Lal, Dennis, Roots, Carla M., Whittle, Belinda, Andrews, Daniel T., Zhang, Yafei, Teoh, Narci C., Sprent, Jonathan, Tze, Lina E., Kucharska, Edyta M., Kofler, Jennifer, Farell, Geoffrey C., Bröer, Stefan, Goodnow, Christopher C., Enders, Anselm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272780/
https://www.ncbi.nlm.nih.gov/pubmed/21423173
http://dx.doi.org/10.1038/ni.2011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272780/
https://www.ncbi.nlm.nih.gov/pubmed/21423173
http://dx.doi.org/10.1038/ni.2011

Ejemplares similares