A Novel Approach for the Simultaneous Analysis of Common and Rare Variants in Complex Traits

Genome-wide association studies (GWAS) have been successful in detecting common genetic variants underlying common traits and diseases. Despite the GWAS success stories, the percent trait variance explained by GWAS signals, the so called “missing heritability” has been, at best, modest. Also, the pr...

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Detalles Bibliográficos
Autores principales: Yuan, Ao, Chen, Guanjie, Zhou, Yanxun, Bentley, Amy, Rotimi, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2012
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273305/
https://www.ncbi.nlm.nih.gov/pubmed/22346348
http://dx.doi.org/10.4137/BBI.S8852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273305/
https://www.ncbi.nlm.nih.gov/pubmed/22346348
http://dx.doi.org/10.4137/BBI.S8852

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