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A Novel Approach for the Simultaneous Analysis of Common and Rare Variants in Complex Traits
Genome-wide association studies (GWAS) have been successful in detecting common genetic variants underlying common traits and diseases. Despite the GWAS success stories, the percent trait variance explained by GWAS signals, the so called “missing heritability” has been, at best, modest. Also, the pr...
Autores principales: | Yuan, Ao, Chen, Guanjie, Zhou, Yanxun, Bentley, Amy, Rotimi, Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273305/ https://www.ncbi.nlm.nih.gov/pubmed/22346348 http://dx.doi.org/10.4137/BBI.S8852 |
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