Intraperitoneal clearance as a potential biomarker of cisplatin after intraperitoneal perioperative chemotherapy: a population pharmacokinetic study

BACKGROUND: Intraperitoneal (IP) perioperative chemotherapy with cisplatin is an interesting option in ovarian cancer treatment. A combination of cisplatin with IP epinephrine (already shown to improve IP and decrease systemic platinum (Pt) exposure) was evaluated using a population pharmacokinetic...

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Detalles Bibliográficos
Autores principales: Royer, B, Kalbacher, E, Onteniente, S, Jullien, V, Montange, D, Piedoux, S, Thiery-Vuillemin, A, Delroeux, D, Pili-Floury, S, Guardiola, E, Combe, M, Muret, P, Nerich, V, Heyd, B, Chauffert, B, Kantelip, J-P, Pivot, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Clinical Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273361/
https://www.ncbi.nlm.nih.gov/pubmed/22173671
http://dx.doi.org/10.1038/bjc.2011.557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273361/
https://www.ncbi.nlm.nih.gov/pubmed/22173671
http://dx.doi.org/10.1038/bjc.2011.557

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