Factor-independent transcription pausing caused by recognition of the RNA–DNA hybrid sequence

Pausing of transcription is an important step of regulation of gene expression in bacteria and eukaryotes. Here we uncover a factor-independent mechanism of transcription pausing, which is determined by the ability of the elongating RNA polymerase to recognize the sequence of the RNA–DNA hybrid. We...

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Detalles Bibliográficos
Autores principales: Bochkareva, Aleksandra, Yuzenkova, Yulia, Tadigotla, Vasisht R, Zenkin, Nikolay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273390/
https://www.ncbi.nlm.nih.gov/pubmed/22124324
http://dx.doi.org/10.1038/emboj.2011.432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273390/
https://www.ncbi.nlm.nih.gov/pubmed/22124324
http://dx.doi.org/10.1038/emboj.2011.432

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