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Factor-independent transcription pausing caused by recognition of the RNA–DNA hybrid sequence
Pausing of transcription is an important step of regulation of gene expression in bacteria and eukaryotes. Here we uncover a factor-independent mechanism of transcription pausing, which is determined by the ability of the elongating RNA polymerase to recognize the sequence of the RNA–DNA hybrid. We...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Molecular Biology Organization
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273390/ https://www.ncbi.nlm.nih.gov/pubmed/22124324 http://dx.doi.org/10.1038/emboj.2011.432 |