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A viral deubiquitylating enzyme targets viral RNA-dependent RNA polymerase and affects viral infectivity

Selective protein degradation via the ubiquitin-proteasome system (UPS) plays an essential role in many major cellular processes, including host–pathogen interactions. We previously reported that the tightly regulated viral RNA-dependent RNA polymerase (RdRp) of the positive-strand RNA virus Turnip...

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Detalles Bibliográficos
Autores principales: Chenon, Mélanie, Camborde, Laurent, Cheminant, Soizic, Jupin, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273391/
https://www.ncbi.nlm.nih.gov/pubmed/22117220
http://dx.doi.org/10.1038/emboj.2011.424