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Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines

Temozolomide (TMZ) is the standard chemotherapeutic agent for human malignant glioma, but intrinsic or acquired chemoresistance represents a major obstacle to successful treatment of this highly lethal group of tumours. Obtaining better understanding of the molecular mechanisms underlying TMZ resist...

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Detalles Bibliográficos
Autores principales: Sun, Stella, Wong, T. S., Zhang, X. Q., Pu, Jenny K. S., Lee, Nikki P., Day, Philip J. R., Ng, Gloria K. B., Lui, W. M., Leung, Gilberto K. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273683/
https://www.ncbi.nlm.nih.gov/pubmed/21979894
http://dx.doi.org/10.1007/s11060-011-0729-8