A model for Escherichia coli chromosome packaging supports transcription factor-induced DNA domain formation

What physical mechanism leads to organization of a highly condensed and confined circular chromosome? Computational modeling shows that confinement-induced organization is able to overcome the chromosome's propensity to mix by the formation of topological domains. The experimentally observed hi...

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Detalles Bibliográficos
Autores principales: Fritsche, Miriam, Li, Songling, Heermann, Dieter W., Wiggins, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273793/
https://www.ncbi.nlm.nih.gov/pubmed/21976727
http://dx.doi.org/10.1093/nar/gkr779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273793/
https://www.ncbi.nlm.nih.gov/pubmed/21976727
http://dx.doi.org/10.1093/nar/gkr779

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