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Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genes
Despite the theoretical bases for the association of topoisomerases and supercoiling changes with transcription and replication, our knowledge of the impact of topological constraints on transcription and replication is incomplete. Although mutation of topoisomerases affects expression and stability...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273821/ https://www.ncbi.nlm.nih.gov/pubmed/21998294 http://dx.doi.org/10.1093/nar/gkr840 |