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Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genes

Despite the theoretical bases for the association of topoisomerases and supercoiling changes with transcription and replication, our knowledge of the impact of topological constraints on transcription and replication is incomplete. Although mutation of topoisomerases affects expression and stability...

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Detalles Bibliográficos
Autores principales: García-Rubio, María L., Aguilera, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273821/
https://www.ncbi.nlm.nih.gov/pubmed/21998294
http://dx.doi.org/10.1093/nar/gkr840