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Molecular basis of differential target regulation by miR-96 and miR-182: the Glypican-3 as a model

Besides the fact that miR-96 and miR-182 belong to the miR-182/183 cluster, their seed region (UUGGCA, nucleotides 2–7) is identical suggesting potential common properties in mRNA target recognition and cellular functions. Here, we used the mRNA encoding Glypican-3, a heparan-sulfate proteoglycan, a...

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Detalles Bibliográficos
Autores principales: Jalvy-Delvaille, Sandra, Maurel, Marion, Majo, Vanessa, Pierre, Nathalie, Chabas, Sandrine, Combe, Chantal, Rosenbaum, Jean, Sagliocco, Francis, Grosset, Christophe F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273822/
https://www.ncbi.nlm.nih.gov/pubmed/22009679
http://dx.doi.org/10.1093/nar/gkr843