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Biochemical Characterization of Recombinant β-Glucosyltransferase and Analysis of Global 5-Hydroxymethylcytosine in Unique Genomes

[Image: see text] 5-Hydroxymethylcytosine (5-hmC) is an enzymatic oxidative product of 5-methylcytosine (5-mC). The Ten Eleven Translocation (TET) family of enzymes catalyze the conversion of 5-mC to 5-hmC. Phage-encoded glucosyltransferases are known to glucosylate 5-hmC, which can be utilized to d...

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Detalles Bibliográficos
Autores principales: Terragni, Jolyon, Bitinaite, Jurate, Zheng, Yu, Pradhan, Sriharsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273966/
https://www.ncbi.nlm.nih.gov/pubmed/22229759
http://dx.doi.org/10.1021/bi2014739