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Novel multi-biotin grafted poly(lactic acid) and its self-assembling nanoparticles capable of binding to streptavidin

Targeted drug delivery requires novel biodegradable, specific binding systems with longer circulation time. The aim of this study was to prepare biotinylated poly(lactic acid) (PLA) nanoparticles (NPs) which can meet regular requirements as well conjugate more biotins in the polymer to provide bette...

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Detalles Bibliográficos
Autores principales: Yan, Hao, Jiang, Weimin, Zhang, Yinxing, Liu, Ying, Wang, Bin, Yang, Li, Deng, Lihong, Singh, Gurinder K, Pan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273980/
https://www.ncbi.nlm.nih.gov/pubmed/22334778
http://dx.doi.org/10.2147/IJN.S24011