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Novel multi-biotin grafted poly(lactic acid) and its self-assembling nanoparticles capable of binding to streptavidin
Targeted drug delivery requires novel biodegradable, specific binding systems with longer circulation time. The aim of this study was to prepare biotinylated poly(lactic acid) (PLA) nanoparticles (NPs) which can meet regular requirements as well conjugate more biotins in the polymer to provide bette...
Autores principales: | Yan, Hao, Jiang, Weimin, Zhang, Yinxing, Liu, Ying, Wang, Bin, Yang, Li, Deng, Lihong, Singh, Gurinder K, Pan, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273980/ https://www.ncbi.nlm.nih.gov/pubmed/22334778 http://dx.doi.org/10.2147/IJN.S24011 |
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